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21c Museum Hotel Louisville

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21c Museum Hotel Louisville, 700 West Main Street, Louisville, KY -(888) 420-1645
Area: Louisville Downtown
(Map)
4.5
HOTEL RATING: 
WONDERFUL
4.5 out of 5 (515 Ratings)
0.4 miles KFC Yum Center
v4 mins driving
t10 mins walking
BOOK ONLINE OR CALL - (888) 420-1645
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The Spotlight on 21c Museum Hotel Louisville

Art, Comfort, and Music Vibes in the Heart of Louisville

Modern and artsy with a luxury twist, the 21c Museum Hotel Louisville is a unique downtown stay just steps from local museums and concert spots. Housed in a historic building, this boutique hotel blends contemporary art with upscale comfort, making it a standout for travelers who want more than just a place to crash after the show. With a full-service spa, on-site art galleries, and stylish rooms featuring 50-inch TVs, mini-bars, and free Wi-Fi, it’s built for both relaxation and inspiration.

Why Concert-goers love it

Location is a big win here — you're within walking distance of several popular venues and nightlife spots, making it easy to catch a show and stroll back safely. The hotel’s vibe is quiet and refined, with soundproofed rooms offering a peaceful retreat after a loud night. With flexible check-in from 4:00 PM and a luxe atmosphere, it’s ideal for unwinding late. On-site bicycle rentals are also great for exploring the local scene during the day.

Who this Hotel is great for

  • Groups of friends looking for a stylish, central base
  • Solo travelers chasing a bucket-list live show and a bit of culture
  • Couples making a romantic weekend of it
  • Fans wanting a quieter place to recharge after the music ends
  • Budget-conscious music fans who still want an upscale experience (watch for deals!)

Food and Drink Options

The hotel’s on-site restaurant, Proof on Main, is a local favorite and serves up creative fare perfect for pre- or post-concert dining. While there’s no 24/7 room service, the location is walkable to late-night eats and bars. Breakfast is available for those who need a slow start after a big night, and minibars in-room are stocked for late-night cravings.

Nightlife Options

From the hotel, you’re just minutes from downtown Louisville’s bar and music scene, including intimate venues and bustling clubs. The hotel bar at Proof on Main offers a great selection of local craft cocktails and often buzzes with pre-show energy. While there’s no live music on-site, the galleries and curated spaces set a cool mood to start your evening.

What People Say

Guests rave about the art-filled atmosphere, friendly staff, and the perfect blend of luxury and culture. Many reviewers highlight the walkable location to museums and music venues, and how quiet the rooms are despite being downtown. The modern design and in-room amenities get consistent praise.

Areas for Improvement

Parking can be a bit pricey, and some guests mention the lighting in rooms is more moody than practical. If you’re planning to crash late and sleep in, pack a sleep mask just in case. Also, while there’s no pool, the on-site sauna and spa help make up for it.

The Bottom Line

For concert-goers who want a stylish, centrally located stay with an artistic edge and quiet comfort, 21c Museum Hotel Louisville hits all the right notes.
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Amenities View More
y
Free Internet
E
Fitness Center
A
Business Center
w
Non Smoking
r
Pets Allowed
q
Accessible
x
Free Breakfast
j
Free Parking
u
Swimming Pool
B
Airport Shuttle
Other Amenities
` Business Center
` Meeting/Banquet Facilities
` Room Service
` Safety Deposit Box
` Air Conditioning
` Bar
` 24-Hour Front Desk
` Elevator
` Hair dryer
` Coffee/tea maker
` Refrigerator
` bathrobes
` Heating
` Wheelchair accessible
` mini bar
` telephone
` alarm clock
` blackout curtains
` 24-hour security
` Concierge services
` Doorman
` Family Rooms
` Free Wi-Fi
` Hair/Beauty Salon
` Massage services
` Restaurant(s)
` Closet
` Daily Housekeeping
` English
` German
` Spanish
` Non-Smoking Rooms Available
` Parking Available
` gift/souvenir shop
` yoga room
` Electric vehicle charging station
` Linens
` Carpeting
` Smoke alarms
` Fire extinguishers
` Staff follow all safety protocols as directed by local authorities
` Shared stationery such as printed menus, magazines, pens, and paper removed
` First aid kit available
` Cashless payment available
` Linens, towels and laundry washed in accordance with local authority guidelines
` Hand sanitizer in guest accommodation and key areas
` Access to health care professionals
` Hygiene certification
` Staff trained in safety protocol
` Temperature check for guests and staff
` Free face masks
` Ticket services
` Contactless check-in/out
` Food delivery
` ATM or cash withdraw on site
` Body thermometer available
` Car rental available
` Complimentary drinking water
` Daily disinfection
` Facilities for disabled guests available
` Fitness center
` Ironing amenities
` Laundry services
` Luggage storage & lockers
` Non-smoking property
` Room towels provided
` Safety chain and/or latch on doors available
` Separate shower/bathtub
` Soundproof rooms available
` Spa services
` Spa/sauna
` Toiletries provided
` Tour services
` TV & Movies/Shows
` Physical/social distancing guidelines
` Protective screen or physical barriers in appropriate areas
` Individually-wrapped food options
` Air conditioning in public area
` Heating in public area
` Trash cans
` Desk/workspace available
` Allergy-free rooms available
` Cleaning products available
` Clothes drying rack
` Pets allowed (charges may apply)
` Parking available (charges may apply)
` Valet parking (charges may apply)
` Xerox/fax in business center

21c Museum Hotel Louisville Guest Reviews

Overall Average Score: 
Wonderful (4.5 out of 5)

Write a review

3

Pleasant - 3 out of 5

Adrian Wed, 14 May 2025

It was ok but didn’t...

Liked: The hotel was in a good location and the art interesting
Disliked: Room was not overly clean, quite dusty and had that dust associated smell with it.

4.5

Wonderful - 4.5 out of 5

Fabian Tue, 13 May 2025

Superb

5

Exceptional - 5 out of 5

Marcia Fri, 2 May 2025

21c museum is a lovely...

3.5

Good - 3.5 out of 5

Kendra Sun, 27 April 2025

They price they charge you...

Liked: The art in the museum!
Disliked: They tell you that you can take pictures and when you get there they tell you something different...

5

Exceptional - 5 out of 5

Stacie Wed, 26 March 2025

Exceptional

5

Exceptional - 5 out of 5

Gina Tue, 11 March 2025

Exceptional

Liked: This hotel is fabulous! The artwork, the staff, the restaurant and location are all top notch!

4.5

Wonderful - 4.5 out of 5

Michel Tue, 11 March 2025

Superb

3

Pleasant - 3 out of 5

Claudia Sun, 9 March 2025

Can do better

Liked: Location, art
Disliked: The facilities were not great, the gym was so extremely dirty

5

Exceptional - 5 out of 5

Courtney Fri, 7 March 2025

Exceptional

5

Exceptional - 5 out of 5

Christopher Sun, 2 March 2025

Quirky art, great service and...

Liked: This 21c is obviously the OG of the 21c hotels. The art displays are phenomenal and the addition of the Night at the Museum perk was a lovely blend of art and bourbon - perfect for Louisville. Also, our room was large and comfortable; the bathroom and its amenities were spa-worthy.

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21c Museum Hotel Louisville 700 West Main Street, Louisville, KY